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2.4 Plasma Membranes

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Phospholipid Structure and Function

Phospholipids are essential components of the cell membrane, providing both structural integrity and selective permeability. These molecules have a unique amphipathic nature, meaning they possess both hydrophilic and hydrophobic regions. The hydrophilic phosphate heads of the phospholipids are oriented toward the external and internal aqueous environments of the cell, interacting with water and other polar molecules. Meanwhile, the hydrophobic fatty acid tails are positioned inward, facing each other and forming a nonpolar, water-repellent core. This arrangement creates the phospholipid bilayer, which acts as a barrier to protect the cell while allowing selective passage of materials. The hydrophobic core restricts the movement of water-soluble substances, making the membrane selectively permeable and helping maintain the internal environment by regulating what enters and exits the cell.

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